How does one configure mutt? There are as many ways as there are mutt users. Five. Haha, that was a little computer humor. Which is to say, terrible, terrible humor. Get used to it. Here is the ultimate guide to getting mutt working the way you want it to work.
Well, this section hasn't become quite the garden of configuration
information I've envisioned yet, but to get you started,
here is my personal .muttrc: sugar.muttrc
and here is my work .muttrc: m2.muttrc